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Index > Protein center > ARID3A(Gene name) > Human
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  • ARID3A (Gene name),
  • AT-rich interactive domain-containing protein 3A (Protein name ),  ARI3A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ARID3A(DRIL1;DRIL3;DRX;E2FBP1);
    Protein name:
    AT-rich interactive domain-containing protein 3A(ARID domain-containing protein 3A);
    Alternative:
    Dead ringer-like protein 1;B-cell regulator of IgH transcription(Bright);E2F-binding protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer. Heterodimer with ARID3B. Interacts with E2F1. Interacts with GTF2I and BTK.
    Function:
    Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation.
    Subcellular Location:
    Nucleus Cytoplasm Shuttles between nucleus and cytoplasm.
    Protein Attributes:
    Sequence length:
    593
    Sequence:
    50:
    MKLQAVMETL | LQRQQRARQE | LEARQQLPPD | PPAAPPGRAR | AAPDEDREPE | 
    100:
    SARMQRAQMA | ALAAMRAAAA | GLGHPASPGG | SEDGPPGSEE | EDAAREGTPG | 
    150:
    SPGRGREGPG | EEHFEDMASD | EDMKPKWEEE | EMEEDLGEDE | EEEEEDYEDE | 
    200:
    EEEEDEEGLG | PPGPASLGTT | ALFPRKAQPP | QAFRGDGVPR | VLGGQERPGP | 
    250:
    GPAHPGGAAH | VAPQLQPPDH | GDWTYEEQFK | QLYELDGDPK | RKEFLDDLFS | 
    300:
    FMQKRGTPVN | RIPIMAKQVL | DLFMLYVLVT | EKGGLVEVIN | KKLWREITKG | 
    350:
    LNLPTSITSA | AFTLRTQYMK | YLYPYECEKR | GLSNPNELQA | AIDSNRREGR | 
    400:
    RQSFGGSLFA | YSPGGAHGML | SSPKLPVSSL | GLAASTNGSS | ITPAPKIKKE | 
    450:
    EDSAIPITVP | GRLPVSLAGH | PVVAAQAAAV | QAAAAQAAVA | AQAAALEQLR | 
    500:
    EKLESAEPPE | KKMALVADEQ | QRLMQRALQQ | NFLAMAAQLP | MSIRINSQAS | 
    550:
    ESRQDSAVNL | TGTNGSNSIS | MSVEINGIMY | TGVLFAQPPA | PTPTSAPNKG | 
    593:
    GGGGGGSSSN | AGGRGGNTGT | SGGQAGPAGL | STPSTSTSNN | SLP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    UniGene:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human ARID domain-containing protein 3A
    Cat.:
    E14648m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human ARID domain-containing protein 3A
    Cat.:
    E14648h
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human ARID domain-containing protein 3A
    Cat.:
    U14648m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ARID domain-containing protein 3A
    Cat.:
    U14648h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human ARID domain-containing protein 3A
    Cat.:
    P14648Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ARID domain-containing protein 3A
    Cat.:
    P14648Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human ARID domain-containing protein 3A
    Monoclonal Antibody for Human ARID domain-containing protein 3A
    Protein for Human ARID domain-containing protein 3A
    Protein for Human ARID domain-containing protein 3A

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The human dead ringer/bright homolog, DRIL1: cDNA cloning, gene structure, and mapping to D19S886, a marker on 19p13.3 that is strictly linked to the Peutz-Jeghers syndrome."
      Kortschak R.D. , Reimann H. , Zimmer M. , Eyre H.J. , Saint R. , Jenne D.E.
      Genomics51:288-292(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    2. 2.
      "A novel E2F binding protein with Myc-type HLH motif stimulates E2F-dependent transcription by forming a heterodimer."
      Suzuki M. , Okuyama S. , Okamoto S. , Shirasuna K. , Nakajima T. , Hachiya T. , Nojima H. , Sekiya S. , Oda K.
      Oncogene17:853-865(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH E2F1;VARIANT SER-556
    3. 3.
      "Molecular cloning and immunologic characterization of DRIL3, a new bright-like ARID protein expressed in both myeloid and lymphoid cells, shares homology to E2FBP1/pRB family complexes."
      Paulin Y.G. , Frank R.T. , Davy E.J.
      Submitted (2004-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Placenta.
    4. 4.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS HIS-36; GLU-320 AND SER-556
      tissue: Placenta.
    6. 6.
      "A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence."
      Peeper D.S. , Shvarts A. , Brummelkamp T. , Douma S. , Koh E.Y. , Daley G.Q. , Bernards R.
      Nat. Cell Biol.4:148-153(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "E2FBP1/DRIL1, an AT-rich interaction domain-family transcription factor, is regulated by p53."
      Ma K. , Araki K. , Ichwan S.J.A. , Suganuma T. , Tamamori-Adachi M. , Ikeda M.-A.
      Mol. Cancer Res.1:438-444(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
    8. 8.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77; SER-81 AND SER-88;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "Induction of immunoglobulin heavy-chain transcription through the transcription factor Bright requires TFII-I."
      Rajaiya J. , Nixon J.C. , Ayers N. , Desgranges Z.P. , Roy A.L. , Webb C.F.
      Mol. Cell. Biol.26:4758-4768(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GTF2I AND BTK;SUBUNIT;DNA-BINDING;MUTAGENESIS OF TYR-325
    10. 10.
      "REKLES is an ARID3-restricted multifunctional domain."
      Kim D. , Probst L. , Das C. , Tucker P.W.
      J. Biol. Chem.282:15768-15777(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ARID3B;DNA-BINDING;SUBUNIT;SUBCELLULAR LOCATION;MUTAGENESIS OF LYS-461; GLY-527; TYR-530; GLY-532 AND LEU-534
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77; SER-81 AND SER-88;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77; SER-88; THR-98; SER-101 AND SER-119;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    17. 17.
      "Solution NMR structure of the ARID domain of human AT-rich interactive domain-containing protein 3A: a human cancer protein interaction network target."
      Liu G. , Huang Y.J. , Xiao R. , Wang D. , Acton T.B. , Montelione G.T.
      Proteins78:2170-2175(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 218-351
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